Ipamorelin / CJC-1295 Blend
฿1,500.00
- Mechanism: GHRP + GHRH synergistic combination; amplified pulsatile GH secretion via dual receptor co-activation
- Format: Co-lyophilized blend, 5mg ipamorelin + 5mg CJC-1295 DAC per vial, >99% purity by HPLC
- Included: Vial + Certificate of Analysis (HPLC + mass spectrum)
For research use only. Not for human or veterinary consumption. In-vitro laboratory use only.
Description
Product Specifications
| Blend | Ipamorelin 5mg + CJC-1295 DAC 5mg (co-lyophilized) |
|---|---|
| Ipamorelin CAS | 170851-70-4 |
| Ipamorelin MW | 711.87 Da |
| CJC-1295 DAC CAS | 863288-34-0 |
| CJC-1295 DAC MW | ~3,367 Da |
| Quantity per vial | 5mg ipamorelin + 5mg CJC-1295 DAC |
| Format | Lyophilized powder (white to off-white) |
| Purity | >99% by HPLC (each component independently verified) |
| Peptide content | ≥90% net peptide (adjusted for water and counter-ions) |
| Verification method | External HPLC chromatography + mass spectrometry |
| Certificate of Analysis | Provided digitally with every shipment |
| Reconstitution | Bacteriostatic water |
| Storage — lyophilized | −20°C, sealed vial, away from moisture and light |
| Storage — in solution | −80°C; use within 30 days; avoid freeze-thaw cycles |
| Shelf life | 24 months from manufacture date (lyophilized, correct storage) |
| Intended use | In-vitro laboratory research only. Not for human or veterinary use. |
Research Background
This vial contains a co-lyophilized blend of two complementary growth hormone secretagogues: Ipamorelin (5mg) and CJC-1295 with Drug Affinity Complex (5mg). Ipamorelin is a selective pentapeptide GHRP that activates the ghrelin/GHS-R1a receptor with high selectivity, stimulating pulsatile GH release without significantly elevating cortisol or prolactin in cell models. CJC-1295 with DAC is a modified GHRH analog that binds covalently to albumin, extending plasma half-life from minutes to approximately one week in vivo.
Together, the two compounds act at distinct receptor targets — GHS-R1a (ipamorelin) and the GHRH receptor (CJC-1295) — producing synergistic amplification of GH secretion in pituitary cell models. This pairing is widely used as a research tool to model sustained, amplified GH pulsatility and to study somatotroph signaling cascades in vitro.
Research Applications
- Synergistic GHS-R1a + GHRHR co-activation studies in primary or cultured pituitary cells
- GH secretion dose-response characterization under combined GHRP/GHRH stimulation
- cAMP and intracellular calcium signaling downstream of GHRH receptor activation
- Comparative potency profiling: ipamorelin vs. GHRP-2, GHRP-6, hexarelin
- Albumin-binding and extended half-life pharmacokinetics modeling (CJC-1295 DAC component)
- Somatotroph receptor expression and desensitization studies under sustained stimulation
- IGF-1 secretion assays in liver cell models following GH pathway activation
Reconstitution Protocol
Allow the vial to reach room temperature before opening. Reconstitute in bacteriostatic water at the desired working concentration; bacteriostatic water is preferred for the DAC component due to the extended reconstitution stability it confers. Do not vortex; swirl gently until the powder is fully dissolved. Filter through a 0.22 μm membrane if sterile conditions are required for cell-based assays. Aliquot into single-use volumes immediately after reconstitution.
Storage and Stability
Store lyophilized vials at −20°C in the original sealed container, protected from moisture and light. Lyophilized material stays stable for up to 24 months from the manufacture date shown on the Certificate of Analysis. Reconstituted solutions should be stored at −80°C and used within 30 days. Avoid repeated freeze-thaw cycles, which degrade both peptide components over time.
What’s Included
- 1 × Ipamorelin / CJC-1295 co-lyophilized vial — 5mg + 5mg
- Independent Certificate of Analysis (HPLC chromatogram + mass spectrum + batch data)
- Batch number and expiry date printed on vial label
- Discreet external packaging with no product name or branding on the exterior
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